Bitcoin’s US-session weakness is deepening as BTC prices on Coinbase trade at a $64 discount to Binance , the largest global crypto exchange

Bitcoin has lost a compounded 3.24% during US stock-market hours since Sept. 21, while prices outside that window advanced 6.07%, according to a CryptoSlate analysis of Binance BTC/USDT trading.

During this period, CryptoQuant’s Coinbase Premium Gap fell to -$64, pointing to weaker demand or heavier selling on the US-focused exchange.

The pattern supports Glassnode’s view that the American trading session has become a source of pressure. But the losses were heavily concentrated in two sessions, while ETF flows on those dates moved in opposite directions, complicating claims of persistent institutional selling.

Across 13 Wall Street cash sessions from Sept. 21 through Oct. 7, Bitcoin fell during eight. According to CryptoSlate's analysis of Binance's data, the largest declines came on Sept. 30 and Oct. 2, when prices dropped 1.86% and 2.65%, respectively, during the 9:30 a.m.-to-4 p.m. New York window.

Remove those two dates and the remaining 11 sessions produce a compounded 1.28% gain.

That influence matters because the headline 3.24% loss can otherwise suggest a steadier deterioration than the data shows. The US session was frequently weak, but much of the cumulative damage came from two sharp moves rather than a uniform pattern of selling.

The data also show that the result changes when the trading window shifts.

From an on-chain analytics and liquidity distribution perspective, developments around "Bitcoin keeps losing ground when Wall Street opens as Coinbase discount deepens" signal important shifts in network participation. Market participants observe that derivative funding metrics, exchange reserve telemetry, and smart contract protocol interactions reflect cautious accumulation alongside disciplined risk hedging across the sector.

Technical research analysts at CryptoAce VIP note that high-density order book clusters and volume-weighted average price (VWAP) benchmarks near recent consolidation floors will serve as pivotal indicators. Market observers are advised to cross-examine telemetry on verified block explorers before making capital allocations.

Editorial Fact-Check & Verification Note: This briefing was curated, corroborated, and synthesized by the CryptoAce VIP Editorial Desk. Readers following "Bitcoin keeps losing ground when Wall Street opens as Coinbase discount deepens" are encouraged to review the full primary source coverage linked below for complete historical context, direct quotes, and official statements.